Therapeutic and Diagnostic Analysis of Cadmium Sulfide Quantum Dots Conjugated with Cysteine, Anticancer Drug and Folate

Background: Nanotechnology is evolving in the field of cancer drug design and therapy. The ultrafine nanoparticles that have a size range 1-10nm are called Quantum Dots. ability to fluorescence has deemed quantum dots as suitable candidate for diagnostic imaging. Upon proper structural arrangement these can be engineered detect specifically cells deliver anticancer agents targeted site cell apoptosis. Aim: Cadmium sulfide (CdS) conjugated with cysteine were prepared by wet method under high temperature pressure Methods: Folic acid receptor shown overexpression multiple types cancers therefore binding folate composite ensures only normal remain unaffected. HeLa opted check activity. Results: Composite showed 23% death first 2 hours delivery. FTIR analysis confirmed conjugation CdS further dacarbazine cysteine. molecules folic attached could measured 2.545× 1018 which 0.996× 〖10〗^22 1.66 x〖 10〗^(20 ) CdS. Similarly, 2.3103 × 1019 doxorubicin Furthermore, cytotoxic nature Sulfide also gives an advantage two way death. Conclusion: specific ligands bind antigens, antibodies, proteins, Receptors etc. used effective diagnosis cancer. They act probe thousands simultaneously using small quantity nanoComposite. Keywords: sulfide, Cancer, dots, Dacarbazine